PAK1IP1 antibody

Catalog No. ABIN7117207

This Rabbit Polyclonal antibody specifically detects PAK1IP1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PAK1IP1 antibody (ABIN7117207)

Target: PAK1IP1 (PAK1 Interacting Protein 1 (PAK1IP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK1IP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PAK1IP1 Antibody

Purpose: PAK1IP1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: PAK1 interacting protein 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PAK1IP1

Target: PAK1IP1 (PAK1 Interacting Protein 1 (PAK1IP1))

Alternative Name: PAK1IP1

Background:

Synonyms: p21-activated protein kinase-interacting protein 1|PAK/PLC-interacting protein 1 (hPIP1)|PAK1-interacting protein 1|WD repeat-containing protein 84|PAK1IP1|PIP1|WDR84

Background: Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42.

Molecular Weight: 44 kDa

Gene ID: 55003

UniProt: Q9NWT1

Pathways: Telomere Maintenance